This study focuses on patients with colon cancer, a type of cancer that develops in the large intestine. The research aims to evaluate a new imaging technique that uses a special radioactive substance called [18F]FAPI-74, which is given as an injection into a vein. This substance is used together with a combined imaging test called PET/CT (Positron Emission Tomography/Computed Tomography) to create detailed pictures of the body.

The main purpose of this research is to determine how well this imaging method can find cancer that has spread to lymph nodes near the colon. During the study, participants will receive a single injection of [18F]FAPI-74 before having the PET/CT scan. The amount of radioactive substance used will not exceed 400 megabecquerels (a unit used to measure radioactivity).

The study will look at different groups of patients: those who have newly diagnosed colon cancer with possible spread to nearby lymph nodes, those who have colon cancer that might be curable despite having spread, and those who are being monitored after previous treatment with suspected return of cancer. The imaging results will help doctors better understand how well this new technique works for detecting the spread of colon cancer.