This study focuses on patients with moderate to severe Rheumatoid Arthritis, a chronic condition that causes joint inflammation, pain, and stiffness. The research compares two medications: MB04 (a proposed new medication) and Enbrel (also known as etanercept). Both medications belong to a group of drugs called tumor necrosis factor alpha inhibitors, which help reduce inflammation in the body.
The purpose of this study is to determine if MB04 works as effectively as Enbrel in treating rheumatoid arthritis. Both medications are given as injections under the skin using pre-filled syringes. During the study, patients will also continue taking methotrexate, which is a standard medication for rheumatoid arthritis treatment.
The treatment period lasts 36 weeks, during which patients receive injections of either MB04 or Enbrel. The maximum daily dose is 50 mg, and the total amount of medication received during the study will not exceed 1800 mg. Throughout the study, doctors will monitor how well the medications work by checking joint symptoms and overall disease activity.



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