This clinical trial is focused on studying the treatment of uncomplicated acute appendicitis, a condition where the appendix becomes inflamed but does not have severe complications. The study aims to compare two different approaches to treating this condition using antibiotics. One approach involves taking antibiotics by mouth, known as oral antibiotics, while the other involves starting with antibiotics given through a vein, known as intravenous antibiotics, followed by oral antibiotics.
The antibiotics being studied in this trial include Levofloxacin, Ertapenem, Moxifloxacin, and Metronidazole. Levofloxacin and Moxifloxacin are taken as tablets, while Ertapenem is given as a solution through an infusion, which is a method of delivering medication directly into the bloodstream. Metronidazole is also taken as a tablet. These medications are all antimicrobial agents, which means they are used to treat infections caused by bacteria.
The purpose of the study is to determine if oral antibiotic treatment alone is as effective as the combination of intravenous and oral antibiotics in treating uncomplicated acute appendicitis. Participants in the study will receive one of these treatments, and their progress will be monitored to see if the appendicitis resolves without the need for surgery and does not return within a year. The study will also look at other factors such as any complications after treatment, the length of hospital stay, and the overall quality of life of the participants during the follow-up period.



Finland