This clinical trial is focused on studying treatments for non-small cell lung cancer, a type of lung cancer that is locally advanced, cannot be surgically removed, or has spread to other parts of the body. The study involves three different treatments: Ociperlimab, an anti-TIGIT antibody, used in combination with Tislelizumab, and a comparison with Pembrolizumab, which is followed by a placebo. The purpose of the study is to compare the overall survival of patients receiving these treatments.
Participants in the study will be randomly assigned to one of two groups. One group will receive Ociperlimab in combination with Tislelizumab, while the other group will receive Pembrolizumab followed by a placebo. The treatments are given as infusions, which means they are administered directly into the bloodstream through a vein. The study will monitor the participants over a period of time to assess the effectiveness of the treatments in improving survival rates.
The trial aims to provide valuable information on how these treatments can help patients with non-small cell lung cancer. By comparing the different treatment options, researchers hope to find the most effective approach for managing this type of cancer. The study will also look at the quality of life of participants and any side effects they may experience during the trial.



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