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Liquid Paraffin

Clinical trials investigating Liquid Paraffin in the provided data focus on a moisturizer study in children with atopic dermatitis, also called eczema. The trial looks at whether a study cream can help prevent relapse, meaning the return of eczema symptoms, compared with a reference cream. It mainly involves children and their parents or legal guardians.

Table of Contents

Trial overview

The available clinical trial data for Liquid Paraffin describe one interventional study in children with atopic dermatitis, also called eczema.[1] The study asked whether a newly developed moisturizer could help prevent relapse of eczema compared with a reference cream.[1]

Condition and population studied

The condition studied was atopic dermatitis/eczema, a common skin problem that can come and go over time.[1] The target population was children, and the study also involved their parents or legal guardians because they helped report when relapse happened.[1]

Study design and phase

This was an interventional study, which means the researchers gave a treatment and then measured the results.[1] The trial was in Phase 3, which is a later stage of research used to test how well a treatment works in a larger group of people.[1] The study enrolled 270 participants and was completed.[1]

What the trial measured

The main outcome was relapse of atopic eczema, measured as a hazard ratio.[1] In simple terms, relapse means the eczema returned and treatment for the study skin area had to be increased.[1] The date of relapse was recorded in an eDiary and then confirmed by the investigator.[1]

Study products compared

The trial summary says the study compared a newly developed moisturizer with a reference cream to see which one better prevented relapse.[1] The listed topical products in the trial record were Essex, Advantan® 0,1% Creme, Linola Fett, ECURAL ® Fettcreme, and Miniderm Duo 20 mg/g + 200 mg/g kräm.[1] The data provided do not give more detail about how each product was used beyond being topical, meaning applied to the skin.[1]

What the available data show

From the provided trial record, the key research question was whether a moisturizer could help prevent eczema relapse in children better than a comparison cream.[1] The study was completed, but no detailed results are included in the source data provided here.[1]

Trial ID Phase Condition studied Status Enrollment
2022-501184-41-00 Phase 3 Atopic dermatitis / eczema Completed 270

FAQ

  • What is being studied in the Liquid Paraffin trial data? The trial studies a moisturizer for preventing eczema relapse in children with atopic dermatitis. It compares a newly developed cream with a reference cream.
  • Who can take part in the study? The target population is children with atopic dermatitis, also called eczema. The study also involves parents or legal guardians, because they help report when a relapse happens.
  • What phase is the trial? The trial is a Phase 3 study. Phase 3 trials usually test whether a treatment works well in a larger group of people.
  • What outcome is the trial measuring? The main outcome is eczema relapse, measured as a hazard ratio. A hazard ratio is a way to compare how often relapse happens in one group versus another over time.
  • How many people were enrolled? The trial enrolled 270 participants. This gives the study a moderate-sized group for testing the moisturizer effect.

Ongoing Clinical Trials on Liquid Paraffin

  • Study on the Effect of a New Moisturiser with Paraffin and Liquid Paraffin on Preventing Eczema Relapse in Children

    Not recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    Germany Sweden

Glossary

  • Atopic dermatitis: A long-term skin condition that causes dry, itchy, inflamed skin. It is often called eczema.
  • Eczema relapse: When eczema symptoms return after they had improved. In this study, relapse means treatment had to be increased for the study area.
  • Moisturiser: A cream or lotion used to help keep the skin hydrated. In this trial, a moisturizer is being tested for relapse prevention.
  • Reference cream: The cream used as a comparison in the study. It helps researchers see whether the new moisturizer works better.
  • Phase 3: A later stage of clinical research that checks how well a treatment works in a larger group of people.
  • Interventional study: A study where researchers give a treatment or product to participants and then measure the results.
  • Hazard ratio: A number used to compare how often an event happens in one group versus another over time.
  • Primary outcome: The main result the study is designed to measure.
  • eDiary: An electronic diary used to record symptoms or events during the study.
  • Investigator: The study doctor or research team member who checks and confirms study information.

References

  1. https://clinicaltrials.gov/study/2022-501184-41-00