Cardiovascular and Arrhythmia Research
Clinical activity is centered on atrial fibrillation in patients at elevated thromboembolic risk, with attention to treatment decisions in those with prior intracranial hemorrhage.
- Atrial fibrillation
- Stroke prevention
- Systemic embolism
The research focus includes balancing anticoagulant therapy against non-antithrombotic approaches in a high-risk cardiac population.
Neurology and Bleeding Risk
Another key area is the management of patients with a history of intracranial hemorrhage, where recurrent bleeding risk is clinically relevant to long-term treatment planning.
- Intracranial hemorrhage
- Hemorrhagic stroke
- Recurrent bleeding risk
This includes interest in outcomes that reflect both ischemic and hemorrhagic cerebrovascular events.
Antithrombotic and Anticoagulation Strategies
The sponsor’s trial portfolio examines edoxaban in relation to nonanticoagulant medical therapy, including antiplatelet monotherapy and no antithrombotic treatment.
- Edoxaban
- Antiplatelet therapy
- Nonanticoagulant medical therapy
These studies address therapeutic choices for patients in whom prevention of embolic events must be considered alongside prior bleeding history.
Multinational Clinical Research
Research operations extend across 10 countries and 65 collaborating sites, supporting enrollment in a geographically broad cardiovascular study network based in Hamilton, Canada.
- International site collaboration
- Recruitment in progress
- Population health research
The active program is organized through the ENRICH-AF Research Project Office.
