Sleep Medicine
Research activity is centered on sleep disorders, with a specific focus on idiopathic Rapid Eye Movement Behavior Disorder and related disturbances of sleep architecture and nocturnal motor control.
- Rapid Eye Movement Behavior Disorder
- Sleep laboratory evaluation
The sponsor’s clinical interest in this area reflects work aimed at understanding and addressing abnormal behaviors occurring during REM sleep.
Neurology
The sponsor is involved in neurological research linked to disorders that affect sleep regulation and motor inhibition during sleep, with attention to the clinical features of isolated RBD.
- Neurological sleep disturbances
- Motor dysregulation during sleep
This area connects clinical investigation of sleep-related neurological symptoms with therapeutic development in a rare neurobehavioral condition.
Therapeutic Development
Clinical research support is directed toward evaluation of piromelatine for its effects on symptoms associated with iRBD, with emphasis on both efficacy and safety in a sleep-disorder setting.
- Piromelatine
- Efficacy and safety assessment
The therapeutic emphasis is on pharmacological management of a disorder with limited treatment options in the sleep medicine field.
