Travere Therapeutics Inc.

Kidney Disease and Proteinuria

Travere Therapeutics Inc. supports research in proteinuric glomerular diseases, with emphasis on focal segmental glomerulosclerosis (FSGS), minimal change disease (MCD), IgA nephropathy (IgAN), IgA vasculitis (IgAV), and Alport syndrome. Its studies focus on renal protection, reduction of proteinuria, and preservation of kidney function.

  • FSGS
  • IgA nephropathy
  • Alport syndrome

Research activity in this area reflects a strong therapeutic interest in chronic glomerular disease and related kidney injury.

Rare Renal Disorders in Pediatric and Adult Populations

The sponsor funds clinical research across both pediatric and adult patients with selected kidney diseases, including conditions marked by persistent proteinuria and progressive loss of renal function. These studies address treatment needs in uncommon nephrology populations.

  • Pediatric kidney disease
  • Renal function preservation
  • Proteinuria control

This area includes ongoing interest in renal disorders where long-term management is central to clinical care.

Classical Homocystinuria

Travere Therapeutics Inc. also funds research in classical homocystinuria (HCU), a rare inherited metabolic disorder associated with elevated homocysteine and methionine levels. The therapeutic focus includes biochemical control and treatment options for patients receiving standard care.

  • Homocystinuria
  • Homocysteine metabolism
  • Inherited metabolic disease

Clinical activity in this field centers on rare disease management and metabolic correction.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on the Safety and Effects of Sparsentan for Children with Proteinuric Kidney Diseases

    Recruiting

    1 1
    Investigated drugs:
    Germany Italy The Netherlands Poland Spain Sweden
  • A study to evaluate the safety and effectiveness of pegtibatinase in patients aged 12 to 65 years with classical homocystinuria.

    Not yet recruiting

    1 1
    Belgium France Germany Ireland Italy Poland +2
  • Study on the Effectiveness and Safety of Sparsentan and Dapagliflozin for Patients with Immunoglobulin A Nephropathy (IgAN)

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Belgium Croatia Czechia Estonia France Germany +5
  • Study on the Effects of Sparsentan and Irbesartan for Patients with Primary Focal Segmental Glomerulosclerosis (FSGS)

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Investigated drugs:
    Belgium Croatia Czechia Denmark Estonia France +6