Alvotech Swiss AG

Gastroenterology and Inflammatory Bowel Disease

Clinical research includes moderate to severe active ulcerative colitis, with interest in biologic treatment pathways and biosimilar development for immune-mediated intestinal inflammation.

  • Ulcerative colitis
  • Biologic therapy
  • Biosimilar medicines

The sponsor’s work in this area is centred on therapeutic options for chronic gastrointestinal inflammation and related immune disease management.

Retinal Diseases and Ophthalmology

Research activity spans diabetic macular edema and broader chorioretinal vascular disease, including conditions associated with retinal fluid accumulation and vascular leakage.

  • Diabetic macular edema
  • Retinal vascular disease
  • Ophthalmic safety

These studies reflect a focus on eye disorders that affect central vision and retinal structure, particularly in diabetic and vascular settings.

Neovascular Eye Disease

Clinical interest extends to neovascular age-related macular degeneration, myopic choroidal neovascularization, retinal vein occlusion, and diabetic retinopathy, covering major causes of sight-threatening retinal neovascularisation.

  • Neovascular age-related macular degeneration
  • Myopic choroidal neovascularization
  • Retinal vein occlusion
  • Diabetic retinopathy

The therapeutic emphasis in this domain is on retinal vascular disorders with a shared pathophysiology of abnormal blood vessel growth and macular involvement.

Biosimilar Development in Specialty Therapeutics

The sponsor’s portfolio includes comparative clinical research for biosimilar candidates across gastroenterology and ophthalmology, supporting treatment areas where targeted biologic therapies are established.

  • Comparative efficacy
  • Ocular safety
  • Specialty biologics

This research landscape connects immune-mediated bowel disease with retinal vascular disorders through the evaluation of advanced therapeutic alternatives.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • A study to compare the efficacy and safety of AVT29 and aflibercept in patients with diabetic macular edema

    Recruiting

    1 1 1 1
    Investigated drugs:
    Bulgaria Czechia Hungary Latvia Poland Slovakia
  • Study Comparing AVT16 and Vedolizumab for Adults with Moderate to Severe Ulcerative Colitis

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Bulgaria Croatia Czechia Greece Hungary Italy +5
  • Study on the Safety and Use of AVT06 (Aflibercept) for Patients with Chorioretinal Vascular Diseases

    Not recruiting

    1 1 1
    Investigated drugs:
    Latvia