Multiple Sclerosis Therapeutics
Immunic AG’s clinical research is centered on multiple sclerosis, with active studies in relapsing multiple sclerosis and relapsing-remitting multiple sclerosis. The programme includes evaluation of disease activity, relapse prevention, and neurological outcomes in adults with active disease.
- Relapsing multiple sclerosis
- Relapsing-remitting multiple sclerosis
- Disease activity assessment
Clinical interest in this area includes treatment of inflammatory disease activity and control of relapse-related progression.
Progressive Multiple Sclerosis
The sponsor also studies progressive forms of multiple sclerosis, with attention to measures of neurodegeneration and structural change in the brain. This area reflects a focus on the unmet therapeutic needs of patients with worsening disability.
- Progressive multiple sclerosis
- Brain atrophy
- Neurodegeneration
Research in this field includes clinical evaluation of outcomes linked to structural preservation and long-term neurological function.
Magnetic Resonance Imaging and Disease Monitoring
Several trials use magnetic resonance imaging to examine inflammatory and structural markers of multiple sclerosis. Imaging-based endpoints are used to characterize lesion burden, brain volume loss, and overall disease activity.
- MRI-based disease assessment
- Whole brain atrophy
- Structural imaging biomarkers
This area supports clinical interest in objective monitoring of central nervous system disease processes.
Drug Interaction and Pharmacokinetics
Immunic AG also funds studies on the pharmacokinetics and drug-drug interaction profile of IMU-838, including interactions relevant to co-administered therapies and common concomitant medications. These studies support the therapeutic development of the compound in multiple sclerosis populations.
- Pharmacokinetic profiling
- Drug-drug interaction studies
- Concomitant medication considerations
Research in this area includes evaluation of absorption, elimination, and compatibility with other treatments used in clinical practice.
