The study looks at people who have a foot deformity caused by osteoarthritis and who need a hind‑ or mid‑foot arthrodesis, a type of surgery that fuses bones to correct the shape and relieve pain. During the operation participants receive either an intravenous dose of tranexamic acid or a control infusion containing sodium chloride as a placebo. The medication is given through a vein while the surgeon is working, and its goal is to reduce bleeding and possibly lower the chance of problems after the operation.
The purpose of the trial is to see whether giving tranexamic acid during surgery changes the rate of post‑operative infections within one year. After the procedure, participants are followed for up to twelve months with check‑ups at two weeks, three months and one year. During these visits doctors look at how the wound is healing, whether the skin has opened up (wound dehiscence), how much blood loss occurred by measuring blood‑type protein levels, and if any additional surgery is needed. Bone healing (fusion) is checked at the final visit using a special imaging test called computed tomography, which produces detailed pictures of the bones. All participants receive the same standard care apart from the study medication, and the study records any infections, wound problems, extra surgeries, and the overall success of the bone fusion.
Finland 
