Vaxigrip is a flu vaccine that helps protect against three different strains of influenza virus. It is called a trivalent inactivated vaccine, which means it contains killed virus particles that cannot cause the flu but help your body build protection against it. The vaccine is given as an injection to help your immune system recognize and fight off the flu if you are exposed to it. This study is looking at how well this standard dose flu vaccine works in people with obesity and how safe it is for them.

Influenza – Influenza is a contagious respiratory illness caused by influenza viruses that infect the nose, throat, and sometimes the lungs. The disease spreads easily from person to person through droplets when infected individuals cough, sneeze, or talk. Symptoms typically appear suddenly and include fever, body aches, headache, tiredness, cough, sore throat, and stuffy or runny nose. The illness usually develops quickly over a few hours and can last from a few days to about two weeks. Most people recover on their own, though some may experience prolonged fatigue after other symptoms improve. The severity can vary from mild discomfort to serious complications, particularly in certain groups of people.

Obesity – Obesity is a medical condition characterized by excessive accumulation of body fat that may negatively affect health. It develops when a person regularly consumes more calories than the body uses for energy over an extended period. The excess energy is stored as fat in various parts of the body, gradually increasing body weight and fat tissue. Obesity typically progresses slowly over months or years as eating and activity patterns remain unchanged. The condition can worsen over time as increased body weight may make physical activity more difficult, potentially leading to further weight gain. Various factors including eating habits, physical activity levels, genetics, and environmental influences contribute to its development.

Type 2 Diabetes – Type 2 diabetes is a chronic condition that affects how the body processes blood sugar, also known as glucose. In this disease, the body either resists the effects of insulin or does not produce enough insulin to maintain normal glucose levels. The condition typically develops gradually over several years, often beginning with a stage called prediabetes where blood sugar levels are higher than normal but not yet high enough to be classified as diabetes. As the disease progresses, the pancreas struggles to produce sufficient insulin to overcome the body’s resistance, leading to increasingly elevated blood sugar levels. Many people may not notice symptoms in the early stages, which can allow the condition to advance undetected. Over time, consistently high blood sugar levels can affect various organs and systems throughout the body.