This clinical trial is focused on patients who need a colonoscopy and are taking medications called antiplatelets or anticoagulants. These medications help prevent blood clots but can increase the risk of bleeding. The study will look at the safety of continuing these medications during a procedure called a cold snare polypectomy, which is used to remove small, non-pedunculated colorectal polyps. The main goal is to see if the risk of bleeding after the procedure is similar whether patients continue their medication or stop it according to current medical guidelines.

The trial will involve several medications, including Apixaban, Clopidogrel, Rivaroxaban, Dabigatran Etexilate, Edoxaban, and Acenocoumarol. These medications are taken orally, meaning they are swallowed in pill form. The study will compare the effects of these medications on bleeding risks during and after the polypectomy procedure. Some patients will continue their medication, while others will stop taking it as per usual medical practice.

The study will last for a period of up to eight weeks for each participant. During this time, participants will undergo the polypectomy procedure and be monitored for any signs of bleeding or other complications. The aim is to ensure that continuing these medications does not increase the risk of significant bleeding compared to stopping them. This information will help doctors make better decisions about managing medications during such procedures in the future.