Rapcabtagene autoleucel is a type of therapy that uses your own immune cells to help fight diseases like rheumatoid arthritis and Sjogren’s disease. In this treatment, some of your immune cells are taken from your body and modified in a lab to better recognize and attack the cells causing your disease. After this modification, the cells are put back into your body to help reduce symptoms and improve your condition. This therapy is being studied to see how safe it is and how well it works for people with difficult-to-treat rheumatoid arthritis and severe Sjogren’s disease that affects organs.

Sjogren’s Syndrome – Sjogren’s Syndrome is an autoimmune disorder characterized by the body’s immune system attacking its own moisture-producing glands. This leads to symptoms such as dry mouth and dry eyes. In severe cases, the disease can involve other organs, including the kidneys, liver, and lungs. The progression of the disease can vary, with some individuals experiencing mild symptoms while others may have more severe organ involvement. Over time, the persistent dryness can lead to complications such as dental decay, oral infections, and vision problems. The disease can also cause fatigue and joint pain.

Rheumatoid Arthritis – Rheumatoid Arthritis is a chronic inflammatory disorder that primarily affects the joints. It occurs when the immune system mistakenly attacks the body’s own tissues, leading to inflammation. This inflammation can cause joint pain, swelling, and stiffness, often affecting the hands and feet. As the disease progresses, it can lead to joint damage and deformities. The inflammation can also affect other parts of the body, including the skin, eyes, lungs, and blood vessels. The severity and progression of symptoms can vary widely among individuals.