This clinical trial is focused on studying the treatment of glabellar lines, which are the vertical lines that appear between the eyebrows when frowning. The study will use a combination of two substances: dantrolene sodium and botulinum toxin type A, known together as the FTP-002/FTP-501 combination. These substances are used to help relax muscles and reduce the appearance of these lines. The trial will also involve the use of sodium chloride as a comparison treatment, often referred to as a placebo.
The purpose of the study is to evaluate the safety and effectiveness of the FTP-002/FTP-501 combination in treating severe glabellar lines. Participants will receive a single injection of the treatment, and the study will compare the results of those receiving the combination treatment to those receiving only FTP-002 or a placebo. The study will monitor how well the treatment works and how long the effects last.
Participants will be observed over a period of time to assess any improvements in the appearance of their glabellar lines. The study aims to determine if the treatment can provide a noticeable reduction in the severity of these lines and how long the improvement lasts. The trial will help to understand the potential benefits and any side effects of using the FTP-002/FTP-501 combination for this cosmetic concern.



Germany