This clinical trial is focused on patients undergoing bariatric surgery, which is a type of surgery aimed at helping with weight loss. The study is investigating the use of a treatment called Opioid-Free Anesthesia during the surgery. This type of anesthesia does not use opioids, which are commonly used pain-relieving drugs. Instead, the study will use a medication called Ketamine Hydrochloride, known by the product name KETOLAR 50 mg/ml solution for injection. Ketamine Hydrochloride is administered through an injection into a vein, a method known as intravenous administration.
The purpose of the study is to evaluate how Opioid-Free Anesthesia affects the oxygen levels in the blood during the first six hours after surgery, compared to conventional anesthesia that includes opioids. This is measured by looking at the Arterial Oxygen Pressure/Inspired Fraction of Oxygen (PaO2/FiO2) ratio, which is a way to assess how well the lungs are working to get oxygen into the blood.
Participants in the study will receive either the Opioid-Free Anesthesia with Ketamine Hydrochloride or a conventional anesthesia. The study will monitor the patients’ oxygen levels and other health indicators during and after the surgery to gather data on the effectiveness and safety of the Opioid-Free Anesthesia approach. The trial aims to provide insights that could improve anesthesia practices for patients undergoing bariatric surgery.



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