Antimicrobial Treatment is used in this study to treat acute appendicitis. The goal is to understand how this treatment affects the gut microbiota, which is the community of microorganisms living in the intestines. The study aims to see how the antimicrobial treatment changes the balance of these microorganisms and how it might influence the development of antibiotic resistance.

Uncomplicated Acute Appendicitis – This condition involves inflammation of the appendix, a small pouch attached to the large intestine. It typically begins with pain near the belly button, which then moves to the lower right side of the abdomen. The pain may be accompanied by nausea, vomiting, and a mild fever. In uncomplicated cases, the appendix has not burst or formed an abscess. The inflammation is usually limited to the appendix itself. If not addressed, it can progress to a more severe form.

Complicated Acute Appendicitis – This form of appendicitis occurs when the appendix becomes severely inflamed and may lead to rupture or the formation of an abscess. The symptoms are similar to uncomplicated appendicitis but tend to be more severe and persistent. The pain may spread throughout the abdomen, and there may be signs of infection such as a high fever. Complications arise when the inflamed appendix bursts, leading to infection in the abdominal cavity. This condition requires more intensive management to prevent further complications.