This clinical trial is focused on studying the effects of a treatment for bronchiectasis, a lung condition where the airways become widened, leading to a build-up of mucus that can cause infections. The treatment being tested involves the inhalation of a 7% hypertonic saline solution, which is a saltwater solution that is more concentrated than normal body fluids. This solution is inhaled before performing a specific type of physiotherapy called ELTGOL, which stands for “Expiration with the Glottis Open in the Lateral position.” This physiotherapy technique helps clear mucus from the lungs.

The purpose of the study is to evaluate how effective this combination of inhaling the hypertonic saline solution once a day and performing the ELTGOL technique twice a day is in helping patients clear mucus from their lungs. The study will compare this treatment to two other approaches: inhaling a less concentrated saltwater solution, known as isotonic saline, once a day along with the ELTGOL technique twice a day, and performing the ELTGOL technique on its own twice a day.

Participants in the study will follow one of these treatment plans over a period of 12 months. Throughout the study, changes in the amount and characteristics of mucus, the frequency of lung infections, and the overall quality of life will be monitored. The study aims to provide insights into the best approach for managing mucus clearance in patients with bronchiectasis, potentially improving their respiratory health and quality of life.