This study focuses on treating patients with Major Depressive Episode combined with insomnia. The research examines the effectiveness of two treatments used together or separately: light therapy and melatonin. Melatonin is a naturally occurring hormone that helps regulate sleep patterns, and in this study, it is used as a prolonged-release tablet containing 2 mg of the active substance.
The purpose of this research is to determine how well these treatments work in reducing depression symptoms when used over an 8-week period. During the study, participants will be divided into different groups, with some receiving melatonin, some receiving light therapy, some receiving both treatments, and others receiving placebo. The treatment period lasts for 8 weeks, with regular check-ups to monitor participants’ progress.
Throughout the study, doctors will assess changes in depression symptoms and sleep patterns. They will use various methods to measure improvements in mood and sleep quality. The total amount of melatonin that participants might receive during the entire study period is 112 mg, taken as daily doses of 2 mg in the form of prolonged-release tablets.



France