This clinical trial is focused on studying the effects of a treatment for glaucoma, a condition that affects the eyes and can lead to vision loss. The treatment being tested is citicoline eye drops, which are being compared to placebo eye drops. The main goal of the study is to determine if citicoline eye drops can better preserve the visual field, which is the area a person can see, in patients with open-angle glaucoma, a common type of glaucoma where the drainage angle for eye fluid remains open.

Participants in the study will receive either the citicoline eye drops or placebo eye drops. The study will last for a period of three years, during which the participants’ eye health and vision will be monitored regularly. The study aims to see if there is a difference in how the vision changes over time between those using citicoline and those using placebo. The researchers will also look at changes in the thickness of certain layers of the retina, the light-sensitive tissue at the back of the eye, using a method called Optical Coherence Tomography (OCT).

This study is important for understanding whether citicoline eye drops can help slow down the progression of vision loss in people with open-angle glaucoma. By comparing the effects of citicoline to placebo, researchers hope to find a more effective way to manage this eye condition and improve the quality of life for those affected by it.