Kamada-AAT for Inhalation is an inhaled form of alpha-1 antitrypsin, a protein that helps protect lung tissue from damage. This medication is designed to treat people who have a genetic condition called Alpha-1 Antitrypsin Deficiency, which can cause lung problems. The medication is inhaled directly into the lungs, where it works to slow down lung damage and help maintain lung function.

Bronchodilator is a type of medication that helps open up the airways in the lungs. In this study, it’s used to help measure how well the lungs are functioning. This medication works by relaxing the muscles around the airways, making it easier to breathe.

Alpha-1 Antitrypsin Deficiency – A genetic condition where the body doesn’t make enough of a protein called alpha-1 antitrypsin, which protects the lungs and liver from damage. The lack of this protein allows enzymes to harm lung tissue over time, leading to breathing problems and lung disease. The condition primarily affects the lungs, causing symptoms such as shortness of breath, wheezing, and decreased lung function. The disease typically develops slowly over years, with early symptoms often appearing in adulthood. People with this condition may experience gradually worsening breathing difficulties, particularly during physical activity.

Chronic Obstructive Pulmonary Disease (COPD) – A progressive lung condition that causes airflow blockage and breathing-related problems. It involves the narrowing of airways, which makes breathing increasingly difficult over time. The condition causes symptoms such as shortness of breath, chronic cough, and increased mucus production. The airways become inflamed and thickened, making it harder to move air in and out of the lungs. People with COPD often experience episodes where symptoms temporarily worsen, known as exacerbations.