This clinical trial studies the effects of corticosteroids in elderly patients undergoing major surgery. The surgical procedures include robotic assisted laparoscopic radical prostatectomy, peripheral vascular surgery, coronary bypass surgery, thoracoscopic lung resection, laparoscopic colorectal surgery, and valve repair or replacement surgery. The study aims to evaluate how moderate doses of corticosteroids affect early recovery after these complex surgical procedures, with a particular focus on muscle weakness.
The treatment involves the use of methylprednisolone (Solu-Medrol), which is given through an intravenous injection. Patients will also receive sodium chloride solution (normal saline) as part of their treatment. The medication will be administered as a single dose on the day of surgery.
During the study, various aspects of recovery will be monitored, including muscle strength, lung function, pain levels, and overall quality of recovery. The study specifically focuses on patients who are 60 years of age or older, as this age group may have different recovery patterns and needs after major surgery.



Belgium