This clinical trial focuses on finding the best timing for starting anticoagulation treatment in patients who undergo heart procedures requiring transseptal puncture (a technique that involves creating a small hole between the upper chambers of the heart). The study specifically looks at two types of procedures: Transcatheter Edge-to-Edge Repair (a minimally invasive procedure to repair a leaking heart valve) and Left Atrial Appendage Closure (a procedure to prevent blood clots in patients with irregular heartbeat).
The study uses two medications: Heparin, which is a blood-thinning medication given by injection, and physiological saline solution, which is a sterile salt water solution used during medical procedures. The main purpose is to determine when it is safest and most effective to start blood-thinning treatment in patients undergoing these heart procedures.
During the study, patients will receive either standard timing of blood-thinning medication or a different timing schedule. The effects will be monitored through various medical examinations, including imaging of the heart and brain, to ensure patient safety and evaluate the effectiveness of different timing approaches. The study will track any complications or adverse events that might occur during and after the procedures.
Poland 
