This clinical trial focuses on treating patients with obstructive colon cancer who have undergone initial treatment with a temporary opening in the abdomen (stoma) to relieve the blockage. The study aims to determine if giving chemotherapy before surgery can improve treatment outcomes compared to giving chemotherapy after surgery.
The treatment involves different combinations of chemotherapy medications including oxaliplatin, fluorouracil, capecitabine, and levoleucovorin. These medications are given either as tablets taken by mouth or as solutions administered through a vein. The chemotherapy combinations used in this study are known as CAPOX and FOLFOX.
The treatment period lasts up to 6 months, during which patients receive regular doses of chemotherapy medications. Throughout the study, patients will need to undergo various medical examinations and tests to monitor their health and response to treatment. The success of the treatment will be measured by how many patients can complete the entire planned treatment sequence.
France 
