FMT Capsules are being studied for their potential to treat immune activation in patients with cirrhosis and ascites. These capsules contain fecal microbiota, which are beneficial bacteria from the gut. The idea is that by introducing these healthy bacteria into the patient’s system, it may help to balance the gut microbiome and reduce immune system activation, which can be a problem in people with liver disease.

Cirrhosis – Cirrhosis is a chronic liver disease characterized by the replacement of healthy liver tissue with scar tissue, which impairs the liver’s ability to function properly. Over time, this scarring can lead to liver failure. The disease progresses slowly and can be caused by various factors, including long-term alcohol abuse, hepatitis infections, and fatty liver disease. As cirrhosis advances, symptoms such as fatigue, jaundice, and swelling in the legs and abdomen may occur. Complications can include portal hypertension, liver cancer, and variceal bleeding. The progression of cirrhosis can vary depending on the underlying cause and the individual’s overall health.

Ascites – Ascites is a condition characterized by the accumulation of fluid in the abdominal cavity, often due to liver disease such as cirrhosis. This fluid buildup can cause abdominal swelling, discomfort, and difficulty breathing. Ascites develops when the liver’s ability to produce proteins and process hormones is impaired, leading to fluid leakage from the blood vessels into the abdominal cavity. The condition can progress to cause infection or kidney problems if not managed. It is often associated with other symptoms of liver disease, such as jaundice and fatigue. The severity of ascites can vary, and it may require medical intervention to manage the symptoms.