This clinical trial is focused on studying a condition known as persistent corneal epithelial defect. This condition affects the surface of the eye, where the outermost layer of the cornea does not heal properly. The study is testing the effectiveness and safety of using insulin eye drops as a treatment. Insulin, commonly known for its role in managing diabetes, is being explored here in a new form as eye drops to help heal the corneal surface.
The purpose of the study is to compare the insulin eye drops with the standard treatment, which involves using autologous serum eye drops. These are eye drops made from a patient’s own blood. The trial will observe how well the insulin eye drops work in healing the corneal defect, especially in cases where the defect is due to nerve damage or long-term eye surface diseases.
Participants in the study will receive either the insulin eye drops or the standard treatment. The study will monitor the healing process over a period of time to see if the corneal defect closes completely. The trial aims to determine how quickly the healing occurs and whether the insulin eye drops are as effective or more effective than the current standard treatment. The study will also look at other factors such as age, sex, and previous eye conditions to understand their impact on the treatment’s success.
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