This clinical trial studies the use of indocyanine green during total thyroidectomy (complete removal of the thyroid gland) to help prevent hypoparathyroidism and hypocalcemia. Hypoparathyroidism is a condition where the body doesn’t produce enough parathyroid hormone, which can lead to low blood calcium levels after thyroid surgery. Hypocalcemia occurs when calcium levels in the blood become too low, which can cause various symptoms.
The study aims to determine if using indocyanine green, a special dye that helps surgeons see blood vessels and tissues more clearly during surgery, can reduce the occurrence of low calcium levels after thyroid surgery. During the procedure, some patients will receive an injection of indocyanine green at a dose of up to 0.5 milligrams per kilogram of body weight, while others will undergo standard surgery without the dye.
The study will monitor patients’ calcium levels in their blood for up to 6 months after surgery. Doctors will check how well the parathyroid glands are working and whether patients develop any signs of low calcium levels. They will also track if using the dye helps surgeons better identify and preserve important structures during the operation.
France 
