Hydroxychloroquine is a medication that is being studied to see if it can help improve pregnancy outcomes in women who have antiphospholipid antibodies. These antibodies can sometimes cause complications during pregnancy, and researchers want to find out if taking hydroxychloroquine can make a positive difference. This medication is often used to treat other conditions like malaria and certain autoimmune diseases, and it works by affecting the immune system. In this trial, the focus is on understanding how it might help pregnant women with specific antibodies have healthier pregnancies.

Antiphospholipid Syndrome – Antiphospholipid Syndrome is an autoimmune disorder characterized by the presence of antiphospholipid antibodies in the blood. These antibodies increase the risk of blood clots forming in veins and arteries, which can lead to complications such as deep vein thrombosis or stroke. In pregnant women, the condition can cause pregnancy-related complications, including recurrent miscarriages, stillbirths, and preterm delivery. The syndrome can also lead to other issues like low platelet counts and heart valve problems. The progression of the disease varies, with some individuals experiencing frequent complications, while others may have long periods without symptoms. The presence of antiphospholipid antibodies is a key factor in the disease’s progression and impact on health.