Based on the provided trial information, which focuses on adjuvant chemotherapy in rectal cancer patients, the typical medications used would be:

FOLFOX is a combination chemotherapy treatment that includes multiple medications working together to kill cancer cells. It’s commonly used as adjuvant therapy after surgery in rectal cancer patients.

Capecitabine is an oral chemotherapy medication that turns into 5-fluorouracil in the body. It works by interfering with cancer cell growth and is often used as adjuvant therapy in rectal cancer treatment.

5-Fluorouracil (also known as 5-FU) is a chemotherapy medication that stops cancer cells from making DNA and RNA, which they need to grow and multiply. It’s a standard treatment option in rectal cancer therapy.

Note: While specific medications aren’t explicitly listed in the source data, these are the standard adjuvant chemotherapy options typically used in rectal cancer treatment when ctDNA (circulating tumor DNA) is detected after surgery.

Rectal Cancer – A disease that begins when cells in the rectum (the last part of the large intestine) start to grow out of control. It typically develops slowly from polyps, which are small growths on the inner lining of the rectum. The disease usually affects the innermost layer of the rectum first, and over time can grow through the rectal wall. Rectal cancer can spread to nearby tissues and lymph nodes, and may eventually reach other parts of the body. The condition often develops without early warning signs, though it may cause changes in bowel habits and rectal bleeding as it progresses.