This clinical trial is focused on studying a condition called Acute Central Retinal Artery Occlusion (CRAO), which is a sudden blockage of blood flow to the main artery of the eye, leading to a quick and painless loss of vision in one eye. The study is testing a treatment called Alteplase, which is a medication that helps dissolve blood clots. The trial will compare the effects of Alteplase with a placebo to see if it can help improve vision in people who have experienced this type of eye blockage.
The purpose of the study is to see if early treatment with Alteplase can help recover vision in patients with Acute Central Retinal Artery Occlusion. Participants in the study will receive either the Alteplase treatment or a placebo. The study will monitor the participants’ vision over a period of time to assess any improvements. The main goal is to achieve a level of vision that is considered normal to mild impairment, as defined by the World Health Organization.
Throughout the study, participants will have their vision checked at different times to see how well they are recovering. The study will also look at other aspects of eye health and vision quality. The trial aims to provide valuable information on whether Alteplase can be an effective treatment for improving vision in patients with this sudden eye condition.
Germany 
