This study focuses on Human Papillomavirus (HPV) infection and examines how the vaccine Gardasil 9 works in the body. HPV is a common virus that can cause various health issues, including certain types of cancer. The study will look at how antibodies produced after vaccination interact with the virus particles in urine samples.

The treatment used in this study is Gardasil 9, which is a vaccine given through intramuscular injection. This vaccine protects against nine different types of HPV. Study participants will receive up to two doses of the vaccine over a period of 12 months. The vaccine contains small particles that look like the virus but cannot cause infection – these are called virus-like particles.

The main purpose of this research is to understand how the body’s immune response to the vaccine works by studying urine samples before and after vaccination. Researchers will examine these samples to see how effectively the vaccine-induced antibodies can prevent the virus from infecting cells. This will help better understand how the vaccine provides protection against HPV infection.