Cromolyn (also known as PHENOGENE-1a) is a medication being studied as an additional treatment for people with ALS (Amyotrophic Lateral Sclerosis). This medication is being tested to see if it can help slow down the progression of symptoms in patients with mild to moderate ALS. Cromolyn has been previously used in other medical conditions, and researchers are now investigating its potential benefits when used alongside other ALS treatments to improve patients’ daily functioning.

Amyotrophic Lateral Sclerosis (ALS) – A progressive neurological disease that affects nerve cells responsible for controlling voluntary muscle movement. The condition causes muscle weakness that starts in specific areas, such as hands, arms, or legs, and gradually spreads to other parts of the body. As motor neurons degenerate, they stop sending messages to the muscles, which leads to muscle weakening, twitching, and inability to move the arms, legs, and body. The disease affects the muscles needed for speaking, swallowing, and breathing. Over time, people with ALS experience increasing difficulty with daily activities requiring muscle control.