This study focuses on people with Relapsing Multiple Sclerosis, a condition where the immune system attacks the protective covering of nerve cells, causing episodes of neurological symptoms. The study compares two medications: remibrutinib, a new oral medication that works by blocking a specific protein called Bruton’s tyrosine kinase, and ocrelizumab, an existing treatment that is given either through an infusion into a vein or as an injection under the skin.
The main purpose of this research is to determine if remibrutinib is as effective as ocrelizumab in controlling disease activity as seen on magnetic resonance imaging (MRI) scans. The study will look at patients who are currently using ocrelizumab and switch them to either continue ocrelizumab or start taking remibrutinib. The study will track participants’ progress for 24 months to compare how well both treatments work.
During the study, participants will receive either remibrutinib tablets taken by mouth or ocrelizumab given through injection or infusion. Doctors will monitor participants’ health through regular check-ups and MRI scans to track any changes in their condition. After the initial 24-month comparison period, all participants will have the opportunity to receive remibrutinib for an extended period.



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