Osimertinib is a targeted therapy medication used to treat non-small cell lung cancer (NSCLC). It works by blocking a specific protein that helps cancer cells grow. It is taken as a tablet and specifically targets cancer cells that have certain genetic mutations in the EGFR gene.

Pemetrexed is a chemotherapy medication that works by stopping cancer cells from making the substances they need to grow and multiply. It is given through an intravenous (IV) infusion and is commonly used to treat non-small cell lung cancer.

Platinum-based chemotherapy (which includes medications like cisplatin or carboplatin) is a type of chemotherapy that works by damaging the DNA of cancer cells, preventing them from dividing and growing. These medications are given through an IV infusion and are often used in combination with other cancer treatments.

Non-Small Cell Lung Cancer – A type of lung cancer that develops in the cells lining the lungs’ air passages and grows more slowly than small cell lung cancer. It begins when healthy cells in the lung change and grow out of control, forming a mass called a tumor. This cancer typically starts in the cells that line the airways of the lungs (bronchi) but can also begin in the smaller branches of the airways (bronchioles) or in the tiny air sacs at the end of the airways (alveoli). The disease can spread from its original location to other parts of the body through the bloodstream or lymphatic system. It accounts for approximately 85% of all lung cancers.