The trial focuses on people with a serious chronic life‑limiting disease who often feel shortness of breath even while resting. The study tests whether a low dose of morphine can reduce this breathlessness compared with a simple saline solution used as a placebo. Both the medication and the placebo are given by a subcutaneous injection, which means the fluid is placed just under the skin.
The purpose of the study is to see if the breathlessness rating improves after the medication is given. Participants are randomly assigned to receive either the morphine or the saline solution, and they are asked to rate how strong their breathlessness feels using a short questionnaire called ESAS-r. The rating is recorded before the injection and again about half an hour and one hour afterward.
During the short observation period, basic safety checks such as breathing rate and level of alertness are monitored, and any side effects are noted. The study follows each participant for a brief time after the injection to ensure safety and to collect the final breathlessness scores.
Sweden 
