Povorcitinib is a medication being studied for long-term safety evaluation. It is an investigational drug that works by targeting specific proteins involved in inflammation. The medication is taken orally and is being tested to understand how well it performs and how safe it is when used over an extended period. This is a continuation study for patients who have previously participated in clinical trials using this medication.

Hidradenitis Suppurativa – A chronic skin condition that causes small, painful lumps to form under the skin, typically in areas where skin rubs together. The condition commonly affects areas with sweat glands, such as armpits, groin, and under the breasts. The lumps can break open, leading to tunnels under the skin and scarring.

Prurigo Nodularis – A skin condition characterized by hard, itchy lumps (nodules) that develop on the skin. These nodules typically appear on the arms, legs, and trunk of the body. The intense itching often leads to a cycle of scratching and further nodule formation.

Vitiligo – A condition where patches of skin lose their color due to the destruction of pigment-producing cells called melanocytes. The depigmented patches can appear anywhere on the body, often starting on the hands, face, or areas around body openings. The patches may gradually become larger over time.