The study involves healthy volunteers and examines how two medicines that are normally used to treat hypertension interact when taken together. One medicine contains ramipril, which helps relax blood vessels, and the other contains indapamide, which helps the body get rid of excess fluid and also lowers blood pressure.
The purpose of the study is to determine whether taking the two medicines at the same time changes how each one is absorbed and processed in the body. Participants will receive a single dose of each medicine alone and then a single dose of both medicines together, with the order chosen at random, while fasting. Blood samples will be collected to assess the pharmacokinetic and bioavailability characteristics of the drugs, and any side effects will be recorded.
The study will evaluate the safety and tolerability of the medicines when used together and will involve only a short period of observation after the single dose administration.



Czechia