68Ga-FAPI is a radioactive imaging agent used in PET/CT scans. It helps doctors see certain types of cells in the body, particularly those associated with cancer and specifically peritoneal metastases (cancer spread to the lining of the abdomen). This tracer attaches to proteins called fibroblast activation proteins (FAP), which are often found in higher amounts around tumors. The imaging helps doctors evaluate how well a patient is responding to chemotherapy treatment.

Note: This trial appears to be an imaging study using this radioactive tracer to monitor treatment response, rather than testing new medications. The chemotherapy mentioned in the trial objective is part of the patients’ standard treatment, not the investigational product.

Peritoneal Metastases – A condition where cancer cells spread to the peritoneum, which is the thin layer of tissue that lines the abdomen and covers most internal organs. The cancer cells form small tumor deposits on the peritoneal surface, which can grow and multiply over time. These metastases typically develop from primary cancers in nearby organs such as the colon, ovaries, or stomach. The condition can cause fluid buildup in the abdomen and may affect the function of abdominal organs. As the disease progresses, the tumor deposits can spread throughout the peritoneal cavity.