This study aims to evaluate the effectiveness of a combination of macrogol 3350 with electrolytes (CLINITRAT) and sodium picosulfate/magnesium citrate (PICOPREP) for bowel preparation before a colonoscopy. A colonoscopy is a procedure where a flexible tube with a camera is used to examine the inside of the large intestine (colon). Proper bowel preparation is essential for a successful colonoscopy, as it allows the doctor to clearly see the intestinal walls.
The study focuses on patients who previously had inadequate bowel preparation during a reference colonoscopy, as measured by the Boston Bowel Preparation Scale (BBPS). The research will determine if this combination of medications provides better cleansing of the intestine compared to a placebo. The effectiveness will be measured by looking at the overall BBPS score, specific scores for different parts of the colon, the rate of polyp detection, and how often the colonoscopy successfully reaches the cecum (the beginning of the large intestine).
Participants in the study will be adults who had insufficient bowel preparation in a previous colonoscopy. The study will also assess how well patients tolerate the preparation regimen through a questionnaire. Good bowel preparation is defined as achieving specific BBPS scores that indicate the colon is clean enough for a thorough examination.
Greece 
