SRSD107 is an investigational medication being studied for preventing blood clots in patients who undergo knee replacement surgery. It is being tested as a potential alternative to currently available blood thinners.

Enoxaparin is a commonly used blood-thinning medication that helps prevent blood clots from forming. It is often given to patients after surgery to reduce the risk of developing dangerous blood clots in the legs or lungs. It belongs to a class of medications called low molecular weight heparins.

Venous thromboembolism (VTE) – A condition where blood clots form in the veins, most commonly in the deep veins of the legs (deep vein thrombosis). These clots can break free and travel through the bloodstream to the lungs, where they can lodge in the pulmonary arteries. The condition often develops during periods of reduced mobility or after surgery. VTE can occur without any noticeable symptoms, though some people may experience leg pain, swelling, or warmth in the affected area. The condition can develop gradually or suddenly, and it’s more common in adults, particularly those over 60.

Deep vein thrombosis (DVT) – A medical condition that occurs when a blood clot forms in one or more of the deep veins in the body, most commonly in the legs. The clots typically form when blood flow slows down or changes, such as during long periods of inactivity or after surgery. DVT can cause leg pain, swelling, and warmth in the affected area, though it can also occur without any symptoms. The condition is more likely to develop after major surgery, especially orthopedic procedures like knee replacement.

Pulmonary embolism (PE) – A blockage in one or more arteries in the lungs, typically caused by blood clots that travel from deep veins elsewhere in the body. The condition develops when a clot breaks free and moves through the bloodstream to the lungs. PE can cause difficulty breathing, chest pain, and rapid heartbeat. The condition can develop suddenly and may occur alongside or following deep vein thrombosis.