This study focuses on women experiencing Preterm Premature Rupture of Membranes, a condition where the protective sac around a developing baby breaks too early in pregnancy. The purpose of the study is to compare different antibiotic treatments to see which is more effective at preventing health problems for the baby and the mother. The medications being studied include ceftriaxone and azithromycin, which will be compared against a combination of amoxicillin and azithromycin.

Participants in the study will receive one of the two antibiotic regimens. One group will receive ceftriaxone through an intravenous, subcutaneous, or intramuscular method, which means the medicine is delivered via an injection into a vein, under the skin, or into a muscle. The other group will receive amoxicillin or azithromycin through oral use, meaning the medicine is taken by mouth. The study follows these patients to monitor the health of the baby and the mother during and after the pregnancy.