This study focuses on patients who have received a kidney transplant and are taking medications to prevent organ rejection. The study will compare two pairs of medications: generic and brand-name versions of tacrolimus (Tacrolimus Ascend and Prograf) and mycophenolate mofetil (Mycophenolate Mofetil Accord and CellCept). These medications are commonly used to suppress the immune system in transplant patients to prevent rejection of the transplanted organ.
The purpose of the study is to determine if the generic versions of these medications work in the same way as the brand-name versions in kidney transplant patients. During the study, participants will take both generic and brand-name versions of their regular medications at different times. The medications will be given as oral capsules or tablets twice daily.
The study will last for 2 months, during which time researchers will monitor how the medications are processed by the body. This involves measuring the amount of medication in the blood at various times after taking the doses. The study will also look at how the medications interact with bacteria in the digestive system and how they are converted in the body.



Norway