This study investigates the treatment of Diabetic Foot Osteomyelitis, which is a serious bone infection that can occur in the feet of people with diabetes. The purpose of the study is to compare a new method of delivering medicine directly to the infected area with traditional methods of taking medicine throughout the entire body. The investigation focuses on a medical device called Stimulan Rapid Cure, which acts as a local antibiotic delivery system to provide medicine specifically at the site of the bone infection.
Participants in the study will be assigned to different groups to receive different types of treatment. One group will receive the Stimulan Rapid Cure device for local antibiotic treatment, meaning the medicine is placed directly where it is needed. The other group will receive systemic antibiotic therapy, which involves taking antibiotics—medicines used to kill bacteria—through the bloodstream via oral pills or intravenous infusions. The comparison medications used in the study include vancomycin hydrochloride, gentamicin, amoxicillin, cefuroxime, metronidazole, doxycycline, ceftriaxone sodium, levofloxacin, ciprofloxacin, clindamycin, piperacillin and tazobactam, meropenem, flucloxacillin, cefalexin, and sulfamethoxazole and trimethoprim.
Finland 
