You will receive treatment with BAY 3713372, which is a medication being tested for tumors with a specific genetic change called MTAP-deletion.

The medication will be given either as a coated tablet that you swallow by mouth or through intravenous infusion, which means it will be delivered directly into your vein.

The treatment is organized in cycles, with each cycle lasting 21 days.

The exact dose and schedule will be determined based on which phase of the study you are in.

If you are in the dose escalation phase, the main goal is to find the safest and most appropriate dose of BAY 3713372.

During this phase, your safety will be closely monitored, especially during the first cycle of 21 days.

Blood samples will be taken to measure how the medication moves through your body and how your body processes it.

The medical team will watch for any side effects or complications that may occur.

If you are in the dose expansion phase, you will receive a dose that has already been tested in earlier participants.

You may receive BAY 3713372 alone or in combination with other standard treatments, depending on which group you are assigned to.

The main purpose of this phase is to see if the medication has an effect on your tumor.

Your tumor will be regularly assessed using imaging tests to check if it is shrinking, staying the same, or growing.

Throughout the entire study, your health and safety will be monitored continuously.

Any side effects, whether mild or serious, will be recorded and assessed by the medical team.

Blood samples will be taken at various times to check how the medication is working in your body.

Your physical condition and ability to perform daily activities will be evaluated using a scale called ECOG performance status.

Your tumor will be evaluated using a standard method called RECIST 1.1, which measures changes in tumor size.

The medical team will determine if your tumor has responded to treatment, including whether it has shrunk, remained stable, or grown.

The time it takes for your tumor to respond to treatment and how long the response lasts will be recorded.

These assessments will help determine if the medication is effective.

You will continue receiving treatment in 21-day cycles for as long as the medication is helping you and not causing unacceptable side effects.

Each cycle follows the same pattern, with regular visits for medication administration, safety checks, and tumor assessments.

The medical team will decide with you when to continue or stop treatment based on how your body responds and your overall health.