This clinical trial is focused on studying the effects of certain medications on preventing further health issues in patients who have experienced an ischemic stroke or have conditions like atherosclerosis, which is a build-up of fats, cholesterol, and other substances in and on the artery walls. The study involves the use of two medications: Colchicine, which is often used to treat inflammation, and Ticagrelor, also known by its code name AZD6140, which helps prevent blood clots. These medications are being tested to see if they can reduce the risk of having another stroke or other major heart-related events.
The purpose of the study is to evaluate how effective low doses of Colchicine and Ticagrelor are in reducing the chances of having another major vascular event, such as a stroke or heart attack. Participants in the study will take these medications over a period of time, and their health will be monitored to see if the medications help in preventing further issues. The study will also include a group of participants who will receive a placebo, which is a substance with no active medication, to compare the effects.
Throughout the study, participants will be asked to take the medications as directed and attend regular check-ups to monitor their health. The study aims to provide valuable information on whether these medications can be a beneficial treatment option for people at high risk of recurrent strokes or heart problems. The results could help in developing better prevention strategies for those with a history of ischemic stroke or related conditions.
France 
