Universitaetsspital Basel

Aortic valve disease and transcatheter aortic valve replacement

Clinical research includes aortic stenosis and peri-procedural management in patients undergoing TAVR, with interest in cardiovascular optimisation around valve intervention.

  • Aortic stenosis
  • Transcatheter aortic valve replacement
  • Beta blocker therapy

The sponsor is also involved in studies examining medication use in the setting of structural heart disease and valve replacement care.

Electrolyte disorders and water balance

Research activity covers hyponatremia and central diabetes insipidus, reflecting a focus on disorders of sodium regulation and fluid homeostasis.

  • Hyponatremia
  • Central diabetes insipidus
  • Plasma sodium concentration

Trials in this area address endocrine and metabolic conditions where maintaining stable electrolyte levels is clinically important.

Musculoskeletal medicine and knee osteoarthritis

The sponsor supports studies in patellofemoral osteoarthritis, with emphasis on cartilage-related treatment approaches for degenerative knee disease.

  • Patellofemoral osteoarthritis
  • Knee pain
  • Cartilage repair

This includes clinical interest in interventions targeting pain, function, and joint preservation in anterior knee osteoarthritis.

Neuroendocrinology and social-emotional processing

Research also extends to oxytocin-related effects on anxiety and recognition of facial and body expressions, indicating interest in neurobehavioral and endocrine mechanisms.

  • Oxytocin
  • Anxiety
  • Facial expression recognition

These studies connect hormonal signalling with emotional processing and behavioural outcomes in human participants.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of beta blockers in patients with aortic stenosis undergoing transcatheter aortic valve replacement

    Recruiting

    1 1 1 1
    Investigated diseases:
    Austria Germany
  • Study on Treating Knee Osteoarthritis with Nasal Cartilage Implantation for Patients with Patellofemoral Osteoarthritis

    Recruiting

    1 1
    Austria Croatia Germany Italy The Netherlands Poland +1
  • Study on the Effects of Empagliflozin in Patients with Euvolemic and Hypervolemic Hyponatremia

    Recruiting

    1 1
    Germany The Netherlands
  • Study on Oxytocin Nasal Spray for Patients with Central Diabetes Insipidus

    Recruiting

    1 1
    Investigated diseases:
    Germany The Netherlands
  • Study on Treating Knee Osteoarthritis with N-TEC Implant for Patients with Patellofemoral Osteoarthritis

    Recruiting

    1 1
    Croatia Germany
  • Study of dabigatran, apixaban and edoxaban for prevention of stroke recurrence in patients with acute ischemic stroke without known atrial fibrillation

    Not yet recruiting

    1 1 1 1
    Investigated diseases:
    Greece Spain