Cardiovascular disease and heart failure
Research activity includes advanced heart failure, chronic right heart failure, and aortic stenosis with myocardial fibrosis. The portfolio also covers interventions linked to transcatheter aortic valve implantation and cardiac regeneration.
- Heart failure and right ventricular dysfunction
- Myocardial fibrosis and fibrotic burden
- Cardiac imaging and structural heart disease
These studies reflect a strong interest in cardiometabolic and structural cardiac conditions with unmet treatment needs.
Kidney disease and genetic nephrology
The sponsor is active in chronic kidney disease linked to Alport syndrome, with emphasis on early renal preservation and inherited renal disorders. The research also addresses progression of kidney involvement in younger patients.
- Alport syndrome
- Chronic kidney disease
- Renal protection and albuminuria
This area highlights involvement in rare kidney diseases and long-term preservation of renal function.
Oncology and neuroendocrine tumors
Clinical research includes neuroendocrine neoplasia, neuroendocrine tumor, and oligometastatic pancreatic cancer, with interest in both systemic and surgical treatment strategies. The oncology portfolio spans aggressive and advanced malignancies.
- Neuroendocrine neoplasia
- Pancreatic cancer
- Multimodal cancer treatment
The sponsor’s oncology work focuses on difficult-to-treat tumors requiring coordinated medical and surgical care.
Neurometabolic and mitochondrial disorders
Research extends to Kearns-Sayre syndrome and related cerebral folate deficiency, indicating interest in rare mitochondrial disease and neurologic metabolic dysfunction. The portfolio also includes cognitive outcomes in systemic disease.
- Kearns-Sayre syndrome
- Mitochondrial disorders
- Cognitive impairment
These studies link rare inherited disease with neurologic and functional outcomes.
Behavioral health and metabolic support
Additional activity covers binge eating disorder and the treatment of iron deficiency in people with chronic heart failure. This combines psychiatric symptom management with supportive care in chronic medical illness.
- Binge eating disorder
- Iron deficiency
- Cognitive function and quality of life
The sponsor’s research interests include both mental health and systemic complications that affect daily functioning.
