Neurology and Neurodegenerative Disease
Research activity includes Parkinson’s disease, Alzheimer’s disease, and progressive supranuclear palsy, with additional interest in brain pathophysiology and long-term neurological treatment outcomes.
- Parkinson’s disease
- Alzheimer’s disease
- Progressive supranuclear palsy
- Brain pathophysiology
The portfolio also extends to neurological symptom control in seizure disorders, including therapies for epilepsy, childhood absence epilepsy, juvenile absence epilepsy, and rapid treatment of prolonged seizure episodes.
Neuromuscular and Autoimmune Neurology
Clinical research covers generalized myasthenia gravis and myelin oligodendrocyte glycoprotein antibody-associated disease, with attention to immune-mediated neurological impairment across pediatric and adult populations.
- Generalized myasthenia gravis
- MOG antibody-associated disease
- Autoimmune neurology
- Pediatric neuromuscular disease
Studies also include rozanolixizumab, zilucoplan, and related long-term safety evaluations in younger patients and adults with chronic neuromuscular disease.
Inflammatory Skin Disease and Dermatology
Therapeutic interest is strong in moderate to severe plaque psoriasis, psoriatic arthritis, hidradenitis suppurativa, atopic dermatitis, and palmoplantar pustulosis.
- Plaque psoriasis
- Psoriatic arthritis
- Hidradenitis suppurativa
- Atopic dermatitis
- Palmoplantar pustulosis
Research also includes juvenile idiopathic arthritis subtypes with skin and joint involvement, reflecting overlap between dermatologic and musculoskeletal inflammation.
Rheumatology and Systemic Autoimmune Disease
Studies address axial spondyloarthritis, psoriatic arthritis, and systemic lupus erythematosus, alongside pediatric inflammatory joint disease such as enthesitis-related arthritis and juvenile psoriatic arthritis.
- Axial spondyloarthritis
- Psoriatic arthritis
- Systemic lupus erythematosus
- Juvenile idiopathic arthritis
Additional work includes immune-targeted approaches in chronic inflammatory disease and evaluation of treatments across adult and pediatric rheumatology settings.
Pediatric and Healthy Volunteer Research
The sponsor also funds studies in healthy participants and healthy volunteers, supporting clinical characterization of investigational therapies across age groups, including children and adolescents.
- Healthy participants
- Healthy volunteers
- Pediatric populations
- Adolescent research
This includes pediatric work in epilepsy, myasthenia gravis, and inflammatory skin disease, with continued attention to age-appropriate treatment use.
