Tyra Biosciences Inc.

Urothelial Cancer and Bladder Cancer

Tyra Biosciences Inc. focuses on clinical research in advanced urothelial carcinoma and non-muscle invasive bladder cancer (NMIBC), with an emphasis on tumors linked to FGFR3 alterations. Its studies address disease settings where targeted treatment strategies are being explored in genitourinary oncology.

  • Advanced urothelial carcinoma
  • Non-muscle invasive bladder cancer (NMIBC)
  • FGFR3 gene alterations

The sponsor’s clinical programme includes both localized bladder cancer and more advanced urinary tract malignancies, reflecting interest in disease control across distinct stages of urothelial disease.

FGFR-Targeted Oncology

The research portfolio is centred on fibroblast growth factor receptor 3 (FGFR3)-driven cancers, including solid tumors with activating molecular changes. This places the sponsor within the field of precision oncology, with attention to biomarker-defined patient groups.

  • FGFR3-altered solid tumors
  • Molecularly selected cancer populations
  • Targeted oncology

Clinical activity extends beyond bladder cancer to other solid tumors carrying the same actionable alteration, indicating a therapeutic interest in shared oncogenic pathways.

Solid Tumor Therapeutics

Tyra Biosciences Inc. also supports research in advanced solid tumors, where the goal is to assess treatment activity in cancer types that remain difficult to manage. The sponsor’s work spans heterogeneous tumor settings unified by a common molecular target.

  • Advanced solid tumors
  • Tumor expansion cohorts
  • Antitumor activity

This area of interest connects oncology drug development with the evaluation of targeted approaches in multiple malignancies, particularly where FGFR3 activation is present.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of TYRA-300-B01 tablets in patients with low grade, intermediate risk non-muscle invasive bladder cancer who have FGFR3 gene changes

    Recruiting

    1 1
    Investigated drugs:
    France Italy Spain
  • Study of TYRA-300 in Adults with Low Grade Upper Tract Urothelial Carcinoma to Assess Efficacy and Safety

    Not yet recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Bulgaria France Spain
  • Study of TYRA-300 for Patients with Advanced Bladder Cancer and Other Solid Tumors with FGFR3 Gene Changes

    Not recruiting

    1 1
    Investigated drugs:
    France Italy Spain