The University Of Birmingham

Haematological Malignancies

Clinical research includes acute myeloid leukaemia, high-risk myelodysplastic syndrome, isolated myeloid sarcoma, polycythaemia vera, and mature B-cell non-Hodgkin lymphoma, with interest in relapsed, refractory, and newly diagnosed disease.

Acute myeloid leukaemia
Myelodysplastic syndrome
Polycythaemia vera
B-cell non-Hodgkin lymphoma

Work in this area spans systemic treatment strategies, targeted therapy, and stem cell transplant-related care.

Paediatric Solid Tumours

The sponsor is active in neuroblastoma, medulloblastoma, rhabdomyosarcoma, Ewing sarcoma, and soft tissue sarcoma, with studies addressing both frontline and relapsed disease.

Neuroblastoma
Medulloblastoma
Ewing sarcoma
Rhabdomyosarcoma
Non-rhabdomyosarcomatous soft tissue sarcoma

Research interest also covers metastatic disease, high-risk disease, and treatment planning for difficult-to-resect tumours.

Paediatric Liver and Germ Cell Tumours

Trials include hepatoblastoma and hepatocellular carcinoma, alongside malignant germ cell tumours and other hepatic malignancies requiring coordinated oncological and surgical management.

Hepatoblastoma
Hepatocellular carcinoma
Malignant germ cell tumour

These studies reflect interest in paediatric hepatology, liver cancer, and tumour control in both resectable and unresectable settings.

Gastrointestinal and Head and Neck Cancers

Research activity includes early-stage colorectal cancer and oropharyngeal cancer, with attention to organ preservation, local control, and functional outcomes.

Early-stage colorectal cancer
Oropharyngeal cancer

These trials involve radiotherapy, surgery, and quality of life considerations in both adult and adolescent populations.

Paediatric Oncology Surgery and Metastatic Disease

The sponsor also supports studies in pulmonary metastasis, renal tumours, and paratesticular rhabdomyosarcoma, with surgical research linked to lymph node dissection and tumour staging.